| ncRNA name | NEAT1 |
| ncRNA Category | lncRNA |
| ID | 283131 |
| Ensembl | ENSG00000245532 |
| Synonyms | VINC; TncRNA; LINC00084; NCRNA00084 |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, normal retinas; RB cell lines Y79, WERI-RB1 and SO‐RB50; RPE cell line ARPE‐19 |
| Methods | transfection, luciferase reporter assay, CCK‐8 assay, transwell assay, annexin V‐FITC/PI staining, RNA immunoprecipitation (RIP), xenograft, qPCR, Western blot |
| Expression pattern | up-regulated |
| Functional description | NEAT1 promotes the development of RB via miR-204/CXCR4 axis. Downregulation of NEAT1 significantly decreased the proliferation and migration but promoted the apoptosis of RB cells. |
| PubMed ID | 30479013 |
| Year | 2019 |
| Title | Long noncoding RNA NEAT1 promotes the growth of human retinoblastoma cells via regulation of miR-204/CXCR4 axis. |
| Drug-related ncRNA | NO |
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